Article
Control of sleep and wakefulness.
Physiological reviews - 1 Jul 2012
Brown Ritchie E, Basheer Radhika, McKenna James T, Strecker Robert E, McCarley Robert W
Abstract excerpt
This review summarizes the brain mechanisms controlling sleep and wakefulness. Wakefulness promoting systems cause low-voltage, fast activity in the electroencephalogram (EEG). Multiple interacting neurotransmitter systems in the brain stem, hypothalamus, and basal forebrain converge onto common effector systems in the thalamus and cortex. Sleep results from the inhibition of wake-promoting systems by homeostatic...
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