Article
Optimisation and validation of methods to assess single nucleotide polymorphisms (SNPs) in archival histological material.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Sept 2004
Andreassen C N, Sørensen F B, Overgaard J, Alsner J
Abstract excerpt
BACKGROUND AND PURPOSE: An increasing amount of evidence indicates that single nucleotide polymorphisms (SNPs) may affect a variety of oncology related phenotypes. Occasionally, it is convenient to base studies addressing genotype-phenotype relationships on historical patient cohorts, from which only archival specimens are available. This study was conducted to validate protocols optimised for assessment of SNPs...
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