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Article

Taqman genotyping assays can be used on decalcified and paraffin-embedded tissue from patients with osteosarcoma.

Pediatric blood & cancer - 1 Jan 2011

Hagleitner Melanie M, Coenen Marieke J H, Jeuken Judith W M, Flucke Uta, Schreuder H W Bart, te Loo D Maroeska W M, Hoogerbrugge Peter M

Abstract excerpt

BACKGROUND: In cancers like osteosarcoma with a 5-year overall survival of 50-60%, archived histological specimens can be a useful source of biological material. However, this material generally has been decalcified and formalin-fixed for many years. In our study, we investigated whether DNA obtained from these tissues can be used for reliable single nucleotide polymorphism (SNP) genotyping. PROCEDURE: We studied...

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PMID: 20848662
DOI: 10.1002/pbc.22654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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