Article
Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping.
BMC medical genomics - 30 May 2012
Abraham Jean E, Maranian Mel J, Spiteri Inmaculada, Russell Roslin, Ingle Susan, Luccarini Craig, Earl Helena M, Pharoah Paul P D, Dunning Alison M, Caldas Carlos
Abstract excerpt
BACKGROUND: The increasing trend for incorporation of biological sample collection within clinical trials requires sample collection procedures which are convenient and acceptable for both patients and clinicians. This study investigated the feasibility of using saliva-extracted DNA in comparison to blood-derived DNA, across two genotyping platforms: Applied Biosystems Taqman™ and Illumina Beadchip™ genome-wide...
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