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Article

Nonmalignant Formalin-Fixed Paraffin-Embedded Tissues as a Source to Study Germline Variants and Cancer Predisposition: A Systematic Review.

Biopreservation and biobanking - 1 Aug 2020

Youssef Omar, Almangush Alhadi, Zidi Yossra H S, Loukola Anu, Carpén Olli

Abstract excerpt

Background: Archived formalin-fixed paraffin-embedded (FFPE) specimens from nonmalignant tissues derived from cancer patients are a vast and potentially valuable resource for high-quality genotyping analyses and could have a role in establishing inherited cancer risk. Methods: We systematically searched PubMed, Ovid MEDLINE, and Scopus databases for all articles that compared genotyping performance of DNA from...

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PMID: 32551987
DOI: 10.1089/bio.2020.0021

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