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Article

Sucrose and IQ induced mutations in rat colon by independent mechanism.

Mutation research - 4 Oct 2004

Hansen Max, Hald Mikkel Thomas, Autrup Herman, Vogel Ulla, Bornholdt Jette, Møller Peter, Mølck Anne-Marie, Lindecrona Rikke, Poulsen Henrik E, Wallin Håkan, Loft Steffen, Dragsted Lars O

Abstract excerpt

Sucrose-rich diets have repeatedly been observed to have co-carcinogenic actions in colon and liver of rats and to increase the number of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induced aberrant crypt foci in rat colon. To investigate a possible interaction between sucrose and IQ on the genotoxicity in rat liver and colon, we gave Big Blue rats a diet containing sucrose (0%, 3.45% or 13.4% w/w) and/or IQ (70...

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Identifiers

PMID: 15450425
DOI: 10.1016/j.mrfmmm.2004.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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