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Article

Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 Loci when expressed on C57BL/6 mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2007

Carlucci Francesco, Cortes-Hernandez Josefina, Fossati-Jimack Liliane, Bygrave Anne E, Walport Mark J, Vyse Timothy J, Cook H Terence, Botto Marina

Abstract excerpt

Extensive evidence indicates that genetic predisposition is a central element in susceptibility to systemic lupus erythematosus both in humans and animals. We have previously shown that a congenic line carrying a 129-derived chromosome 1 interval on the C57BL/6 background developed humoral autoimmunity. To further dissect the contribution to autoimmunity of this 129 interval, we have created six subcongenic...

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Identifiers

PMID: 17277141
DOI: 10.4049/jimmunol.178.4.2352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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