Article
Genetic localization and transmission of the mouse osteopetrotic grey-lethal mutation.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 1999
Vacher J, Bernard H
Abstract excerpt
The grey-lethal (gl) mouse is the most relevant animal model for recessive osteopetrosis, a genetic defect affecting bone resorption. To localize the gl gene, two novel backcrosses between the gl mutant strain GL/Le dlJ +/+ gl and with the Mus spretus or the Mus m. molossinus have been generated and typed with 19 DNA markers representative of genes or microsatellites. In the Mus m. molossinus backcross, the gl...
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