Article
Multidrug resistance in hematological malignancy.
The journal of medical investigation : JMI - 1 Aug 2003
Hirose Masao, Hosoi Eiji, Hamano Shuichi, Jalili Ali
Abstract excerpt
The recent treatment of hematological malignancies appears to be unsatisfactory in child and adult patients with acute myeloid leukemia and adult patients with acute lymphocytic leukemia. A major problem in the treatment of leukemia is caused by the development of drug resistance to chemotherapeutic agents, which is already present at diagnosis or after chemotherapy as a minimal residual disease, their resistance...
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