Article
Androgen deprivation therapy for prostate cancer: current status and future prospects.
The Prostate - 1 Dec 2004
Miyamoto Hiroshi, Messing Edward M, Chang Chawnshang
Abstract excerpt
Androgens play a major role in promoting the development and progression of prostate cancer. As a result, androgen ablation or blockade of androgen action through the androgen receptor (AR) has been the cornerstone of treatment of advanced prostate cancer. Different strategies involving this hormonal therapy produce a significant clinical response in most of the patients, but most responders eventually lose...
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