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Article

Targeting androgen receptor-independent pathways in therapy-resistant prostate cancer

27 Nov 2018

Abstract excerpt

Since androgen receptor (AR) signaling is critically required for the development of prostate cancer (PCa), targeting AR axis has been the standard treatment of choice for advanced and metastatic PCa. Unfortunately, although the tumor initially responds to the therapy, treatment resistance eventually develops and the disease will progress. It is therefore imperative to identify the mechanisms of therapeutic...

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PMID: 30775252
DOI: 10.1016/j.ajur.2018.11.002

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