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Article

Dissecting major signaling pathways in prostate cancer development and progression: Mechanisms and novel therapeutic targets.

The Journal of steroid biochemistry and molecular biology - 1 Feb 2017

Ramalingam Senthilmurugan, Ramamurthy Vidya P, Njar Vincent C O

Abstract excerpt

Prostate cancer (PCa) is the most frequently diagnosed non-cutaneous malignancy and leading cause of cancer mortality in men. At the initial stages, prostate cancer is dependent upon androgens for their growth and hence effectively combated by androgen deprivation therapy (ADT). However, most patients eventually recur with an androgen deprivation-resistant phenotype, referred to as castration-resistant prostate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27481707
DOI: 10.1016/j.jsbmb.2016.07.006
PMCID: PMC7371258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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