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Article

The development of androgen-independent prostate cancer.

Nature reviews. Cancer - 1 Oct 2001

Feldman B J, Feldman D

Abstract excerpt

The normal prostate and early-stage prostate cancers depend on androgens for growth and survival, and androgen ablation therapy causes them to regress. Cancers that are not cured by surgery eventually become androgen independent, rendering anti-androgen therapy ineffective. But how does androgen independence arise? We predict that understanding the pathways that lead to the development of androgen-independent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11900250
DOI: 10.1038/35094009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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