Mechanisms of prostate cancer progression to androgen independence.

Abstract excerpt

Prostate cancer is a major health problem in the United States and worldwide. In 2007, more than 27,000 men were estimated to have died from prostate cancer in the United States alone. Although important advances have been made in the diagnosis and treatment of prostate cancer, therapies focused on the removal or inhibition of androgen action remain the most important components of therapy for individuals with...

Topics

• Androgen Antagonists
• Androgens
• Antineoplastic Agents, Hormonal
• Cell Communication
• Disease Progression
• Drug Resistance, Neoplasm
• Humans
• Male
• Models, Biological
• Mutation
• Neoplasms, Hormone-Dependent