Article
The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm.
The Journal of biological chemistry - 3 Dec 2004
Pierreux Christophe E, Vanhorenbeeck Vinciane, Jacquemin Patrick, Lemaigre Frédéric P, Rousseau Guy G
Abstract excerpt
During development, the endoderm gives rise to several organs, including the pancreas and liver. This differentiation process requires spatial and temporal regulation of gene expression in the endoderm by a network of tissue-specific transcription factors whose elucidation is far from complete. These factors include the Onecut protein hepatocyte nuclear factor-6 (HNF-6), which controls pancreas and liver...
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