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Article

The onecut transcription factor HNF6 is required for normal development of the biliary tract

15 Apr 2002

Abstract excerpt

During liver development, hepatoblasts differentiate into hepatocytes or biliary epithelial cells (BEC). The BEC delineate the intrahepatic and extrahepatic bile ducts, and the gallbladder. The transcription factors that control the development of the biliary tract are unknown. Previous work has shown that the onecut transcription factor HNF6 is expressed in hepatoblasts and in the gallbladder primordium. We now...

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PMID: 11934848
DOI: 10.1242/dev.129.8.1819

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