Article
Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification.
Development (Cambridge, England) - 1 Nov 1999
Barbacci E, Reber M, Ott M O, Breillat C, Huetz F, Cereghini S
Abstract excerpt
Genetic and molecular evidence indicates that visceral endoderm, an extraembryonic cell lineage, is required for gastrulation, early anterior neural patterning, cell death and specification of posterior mesodermal cell fates. We show that variant Hepatocyte Nuclear Factor 1 (vHNF1), a homeodomain-containing transcription factor first expressed in the primitive endoderm, is required for the specification of...
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