Article

The transcription factor FoxO1 is required for the establishment of the human definitive endoderm

2020-12-22

Abstract excerpt

The transcription factor FoxO1 has been shown to dynamically regulate cell fate across diverse cell types. Here, we employ a human induced pluripotent stem cell (hiPSC)-to-hepatocyte differentiation system that recapitulates the process of hepatocyte specification and differentiation in the human embryo to investigate FoxO1 as a participant in the molecular events required to execute the initial stages of liver de...

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Literature Corpus work: 252d8c37-a7d4-5d56-8ffa-7a10c548df17
DOI: 10.1101/2020.12.22.423976

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