Article
Antigen-specific (p30) mouse CD8+ T cells are cytotoxic against Toxoplasma gondii-infected peritoneal macrophages.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1992
Kasper L H, Khan I A, Ely K H, Buelow R, Boothroyd J C
Abstract excerpt
The importance of CD8+ T cells in immunity against Toxoplasma gondii is now well recognized. The mechanism by which these CD8+ T cells are able to confer this immunity is not yet understood. To examine the Ag specificity of this response, immune splenocytes from mice immunized with p30, a major surface parasite Ag, were evaluated for their ability to lyse peritoneal macrophages infected with three different...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Protozoan
- Base Sequence
- CD8 Antigens
- Immunization
- Macrophages
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Molecular Sequence Data