Article
Toxoplasma gondii induction of interleukin-12 is associated with acute virulence in mice and depends on the host genotype.
Veterinary parasitology - 12 Sept 2001
Schade B, Fischer H G
Abstract excerpt
The intracellular parasite Toxoplasma gondii can influence host resistance by modulating immune functions in various cell types. The stimulation of interleukin (IL)-12 production in macrophages, dendritic cells and neutrophils by T. gondii has been implicated to be important for skewing anti-parasite immunity early after infection as well as in mediating the pathologic effects induced by the parasite. The present...
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