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Estrogen receptor-alpha gene haplotype is associated with primary knee osteoarthritis in Korean population.

Arthritis research & therapy - 1 Jan 2004

Jin Sheng-Yu, Hong Seung-Jae, Yang Hyung In, Park Sang-do, Yoo Myung-Chul, Lee Hee Jae, Hong Mee-Suk, Park Hae-Jeong, Yoon Seo Hyun, Kim Bum-Shik, Yim Sung-Vin, Park Hun-Kuk, Chung Joo-Ho

Abstract excerpt

Estrogen and estrogen receptors (ERs) are known to play important roles in the pathophysiology of osteoarthritis (OA). To investigate ER-alpha gene polymorphisms for its associations with primary knee OA, we conducted a case-control association study in patients with primary knee OA (n = 151) and healthy individuals (n = 397) in the Korean population. Haplotyping analysis was used to determine the relationship...

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Identifiers

PMID: 15380041
DOI: 10.1186/ar1207
PMCID: PMC546279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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