The single-nucleotide polymorphism (SNP) of tumor necrosis factor α -308G/A gene is associated with early-onset primary knee osteoarthritis in an Egyptian female population.

doi:10.1007/s10067-017-3727-1

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The single-nucleotide polymorphism (SNP) of tumor necrosis factor α -308G/A gene is associated with early-onset primary knee osteoarthritis in an Egyptian female population.

Clinical rheumatology - 1 Nov 2017

Abdel Galil Sahar M, Ezzeldin Nillie, Fawzy Faten, El-Boshy Mohamed

Abstract excerpt

The objective of the present study is to investigate if there is a potential association between the single-nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha gene (TNF-α -308G/A, rs1800629) and the susceptibility to and severity of early-onset knee osteoarthritis in the Egyptian female population. Genotype distributions and allelic frequencies of TNF-α -308G/A polymorphism were investigated in...

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PMID: 28695434
DOI: 10.1007/s10067-017-3727-1

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