Article
Association of estrogen receptor-alpha single-nucleotide polymorphism (codon 594 G-->A) and Thai patients affected by knee osteoarthritis.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Dec 2009
Tawonsawatruk Tulyapruek, Trachoo Objoon, Channoom Thanaphot, Sura Thanyachai, Eu-ahsunthornwattana Jakris, Woratanarat Patarawan, Wajanavisit Wiwat
Abstract excerpt
BACKGROUND: Estrogen receptor-alpha single-nucleotide polymorphism (ER-alpha SNP) has previously shown its susceptibility to knee osteoarthritis (OA) but this association cannot be applied to ethnic groups with different genetic backgrounds. OBJECTIVE: To characterize the genetic association between ER-alpha SNP and knee OA in the Thai. MATERIAL AND METHOD: A case-control study was conducted at Ramathibodi...
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