Article
Biological activity of the virulence factor cagA of Helicobacter pylori.
Chinese medical journal - 1 Sept 2004
Zhu Yong-liang, Zheng Shu, Qian Ke-da, Fang Ping-chu
Abstract excerpt
BACKGROUND: China is one of the countries with the highest incidence of H. pylori and more than 9090 isolates possessed the cagA gene. This study was to evaluate the biological activity of the H. pylori virulence factor cagA isolated from Chinese patients. METHODS: cagA DNA fragments were amplified from the genomic DNA and subsequently cloned into the mammalian expression vector for cell transfection and DNA...
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