Article
Wide range of quasispecies diversity during primary hepatitis C virus infection.
Journal of virology - 1 Apr 2005
Herring Belinda L, Tsui Rose, Peddada Lorraine, Busch Michael, Delwart Eric L
Abstract excerpt
Hepatitis C virus (HCV) infections may be initiated by multiple infectious particles, resulting in a genetically heterogeneous viral population, or by a single particle, leading to a clonal population in the initial stage of infection. To determine which of these scenarios is most common, we evaluated the genetic diversity of HCV quasispecies in 12 seronegative subjects with primary infection following community...
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