Article
Epidermal growth factor gene (EGF) polymorphism and risk of melanocytic neoplasia.
The Journal of investigative dermatology - 1 Oct 2004
James Michael R, Hayward Nicholas K, Dumenil Troy, Montgomery Grant W, Martin Nicholas G, Duffy David L
Abstract excerpt
A common single nucleotide polymorphism (SNP) in the 5' untranslated region (5'UTR) of the epidermal growth factor (EGF) gene modulates the level of transcription of this gene and hence is associated with serum levels of EGF. This variant may be associated with melanoma risk, but conflicting findings have been reported. An Australian melanoma case-control sample was typed for the EGF+61A>G transversion...
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