Article
Association between functional polymorphism in EGF gene and malignant melanoma.
Lancet (London, England) - 2 Feb 2002
Shahbazi Majid, Pravica Vera, Nasreen Najma, Fakhoury Hana, Fryer Anthony A, Strange Richard C, Hutchinson Peter E, Osborne Joy E, Lear John T, Smith Andrew G, Hutchinson Ian V
Abstract excerpt
BACKGROUND: Malignant melanoma, the most serious cutaneous malignancy, has attracted substantial attention because of its rapidly increasing incidence and the poor prognosis of some tumours. Little is known of the genetic factors that mediate susceptibility to, and outcome of, sporadic malignant melanoma. Because of its role in mitogenesis, which is especially relevant to wound healing, tumorigenesis, and...
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