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Article

Role of the EGF +61A>G polymorphism in melanoma pathogenesis: an experience on a large series of Italian cases and controls.

BMC dermatology - 22 Jul 2009

Casula Milena, Alaibac Mauro, Pizzichetta Maria A, Bono Riccardo, Ascierto Paolo A, Stanganelli Ignazio, Canzanella Sergio, Palomba Grazia, Zattra Edoardo, Palmieri Giuseppe

Abstract excerpt

BACKGROUND: A single nucleotide polymorphism (61A>G) in the epidermal growth factor (EGF) gene has been implicated in both melanoma pathogenesis and increased melanoma risk. To further evaluate this association, we conducted a case-control study in a clinic-based Italian population. METHODS: Individuals with less than 10 (N = 127) or more than 100 (N = 128) benign nevi, and patients with cutaneous melanoma (N =...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19624835
DOI: 10.1186/1471-5945-9-7
PMCID: PMC2719594

Genes

EGF

Provenance

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