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Article

A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis.

The Journal of biological chemistry - 19 Nov 2004

Li Ai-Ling, Li Hui-Yan, Jin Bao-Feng, Ye Qi-Nong, Zhou Tao, Yu Xiao-Dan, Pan Xin, Man Jiang-Hong, He Kun, Yu Ming, Hu Mei-Ru, Wang Jie, Yang Song-Cheng, Shen Bei-Fen, Zhang Xue-Min

Abstract excerpt

Although eukaryotic translation initiation factor 5A (eIF5A) was originally designated as an "initiation factor," recent data have shown it to be also involved in apoptosis. However, the actual function of eIF5A in apoptosis is still unknown. In this study, we performed yeast two-hybrid screens to identify eIF5A-interacting proteins to help us understand the mechanisms of eIF5A. Our results demonstrated that...

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Identifiers

PMID: 15371445
DOI: 10.1074/jbc.M407165200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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