Article
Effect of IPP5, a novel inhibitor of PP1, on apoptosis and the underlying mechanisms involved.
Biotechnology and applied biochemistry - 7 Dec 2009
Zeng Qiyan, Huang Yu, Zeng Linjie, Lan Xiuwan, Huang Yongqi, He Shujia, Zhang Hong
Abstract excerpt
Genes encoding apoptosis-inducing proteins are postulated to be candidate tumour suppressors. The identification of such proteins may benefit the early diagnosis and therapy of tumours. In the present study, we characterized the function of a novel human BMSC (bone marrow stromal cell)-derived protein {IPP5 [inhibitor-5 of PP1 (protein phosphatase 1)]} by large-scale random sequencing of a human BMSC cDNA...
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