Article
Inhibitory helix-loop-helix transcription factors Id1/Id3 promote bone formation in vivo.
Journal of cellular biochemistry - 1 Oct 2004
Maeda Yukiko, Tsuji Kunikazu, Nifuji Akira, Noda Masaki
Abstract excerpt
Bone formation is under the control of a set of transcription factors. Ids are inhibitory helix-loop-helix (HLH) transcription factors and expression of Id genes in osteoblasts is under the control of calciotropic agents such as BMP and vitamin D. However, the function of Ids during bone formation in vivo has not yet been elucidated. We, therefore, examined the role of Id1 and Id3 in the regulation of bone...
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