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Article

The Circadian Gene Clock Regulates Bone Formation Via PDIA3

24 Nov 2016

Abstract excerpt

ABSTRACT The expression patterns of clock-controlled genes (ccgs) are regulated by circadian rhythm, which is a major regulatory and physiological mechanism tied to the solar day. Disruptions in circadian rhythm contribute to the development of cardiovascular diseases, cancer, metabolic syndromes, and aging. It has been reported that bone remodeling is also regulated by circadian rhythm. However, the molecular...

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PMID: 27883226
DOI: 10.1002/jbmr.3046

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