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Article

Sugar recognition by the lactose permease of Escherichia coli.

The Journal of biological chemistry - 19 Nov 2004

Vázquez-Ibar José Luis, Guan Lan, Weinglass Adam B, Verner Gill, Gordillo Ruth, Kaback H Ronald

Abstract excerpt

Biochemical, luminescence and mass spectroscopy approaches indicate that Trp-151 (helix V) plays an important role in hydrophobic stacking with the galactopyranosyl ring of substrate and that Glu-269 (helix VIII) is essential for substrate affinity and specificity. The x-ray structure of the lact...

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Identifiers

PMID: 15364943
DOI: 10.1074/jbc.M407408200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15364943-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Sugar recognition by the lactose permease of Escherichia coli.PMID 15364943Read ↗

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Ligand-induced movement of helix X in the lactose permease from Escherichia coli: a fluorescence quenching study.Semantic proximity Read ↗

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