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Article

An analysis of suppressor mutations suggests that the two halves of the lactose permease function in a symmetrical manner.

The Journal of biological chemistry - 17 Oct 1997

Pazdernik N J, Cain S M, Brooker R J

Abstract excerpt

A conserved motif, GXXX(D/E)(R/K)XG[X](R/K)(R/K), is located in loop 2/3 and loop 8/9 in the lactose permease, and also in hundreds of evolutionarily related transporters. The importance of conserved residues in loop 8/9 was previously investigated (Pazdernik, N. J., Jessen-Marshall, A. E., and Brooker, R. J. (1997) J. Bacteriol. 179, 735-741). Although this loop was tolerant of many substitutions, a few...

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Identifiers

PMID: 9334175
DOI: 10.1074/jbc.272.42.26110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An analysis of suppressor mutations suggests that the two halves of the lactose permease function in a symmetrical manner.PMID 9334175Read ↗

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