Article
Geographical north-south decline in DNASE1*2 in Japanese populations.
Human biology - 1 Feb 2001
Takeshita H, Yasuda T, Nakashima Y, Mogi K, Kishi K, Shiono H, Sagisaka K, Yuasa I, Nishimukai H, Kimura H
Abstract excerpt
Allele frequencies for human deoxyribonuclease I (DNase I) phenotypes were determined using blood samples from about 2000 Japanese subjects living in nine prefectures, and compared with one another. DNase I phenotyping was performed principally using isoelectric focusing electrophoresis and activity staining. The DNase I system was shown to have enhanced potential for anthropologic, genetic, and clinical studies...
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