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Article

Human serum deoxyribonuclease I (DNase I) polymorphism: pattern similarities among isozymes from serum, urine, kidney, liver, and pancreas.

American journal of human genetics - 1 Jul 1990

Kishi K, Yasuda T, Ikehara Y, Sawazaki K, Sato W, Iida R

Abstract excerpt

We have devised a zymogram method with high sensitivity and resolution for investigating molecular heterogeneity and genetic polymorphism of deoxyribonuclease I. A combination technique of polyacrylamide-gel isoelectric-focusing electrophoresis and the newly developed zymogram method have led to the discovery of genetic polymorphism of human serum DNase I. Family studies showed that the three common...

Topics

Deoxyribonuclease I
Electrophoresis, Polyacrylamide Gel
Humans
Isoenzymes
Kidney
Liver
Organ Specificity
Pancreas
Phenotype
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Open in PubMed Open full text

Identifiers

PMID: 2349940
PMCID: PMC1683738

Genes

DNASE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2349940-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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