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Article

Rolling blackout, a newly identified PIP2-DAG pathway lipase required for Drosophila phototransduction.

Nature neuroscience - 1 Oct 2004

Huang Fu-De, Matthies Heinrich J G, Speese Sean D, Smith Mark A, Broadie Kendal

Abstract excerpt

The rolling blackout (rbo) gene encodes an integral plasma membrane lipase required for Drosophila phototransduction. Photoreceptors are enriched for the RBO protein, and temperature-sensitive rbo mutants show reversible elimination of phototransduction within minutes, demonstrating an acute requirement for the protein. The block is activity dependent, indicating that the action of RBO is use dependent....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15361878
DOI: 10.1038/nn1313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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