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Article

Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors.

Neuron - 1 Apr 2001

Hardie R C, Raghu P, Moore S, Juusola M, Baines R A, Sweeney S T

Abstract excerpt

The trp (transient receptor potential) gene encodes a Ca2+ channel responsible for the major component of the phospholipase C (PLC) mediated light response in Drosophila. In trp mutants, maintained light leads to response decay and temporary total loss of sensitivity (inactivation). Using genetically targeted PIP2-sensitive inward rectifier channels (Kir2.1) as biosensors, we provide evidence that trp decay...

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Share to Biosensing Techniques
Share to Calcium Channels
Share to Calcium Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphatidylinositol 4,5-Diphosphate

Share to Photoreceptor Cells, Invertebrate

Share to Potassium Channels, Inwardly Rectifying

Share to Transient Receptor Potential Channels

Share to Vision, Ocular

Source

Identifiers

PMID: 11343651
DOI: 10.1016/s0896-6273(01)00269-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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