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Article

Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase.

Nature - 19 Jan 1995

Wu L, Niemeyer B, Colley N, Socolich M, Zuker C S

Abstract excerpt

CDP-diacylglycerol synthase (CDS) is an enzyme required for the regeneration of the signalling molecule phosphatidylinositol-4,5-bisphosphate (PtdlnsP2) from phosphatidic acid. A photo-receptor cell-specific isoform of CDS from Drosophila is a key regulator of phototransduction, a G-protein-coupled signalling cascade mediated by phospholipase C. cds mutants cannot sustain a light-activated current as a result of...

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PMID: 7816135
DOI: 10.1038/373216a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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