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Article

Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships.

Human molecular genetics - 1 Oct 2004

Nash Matthew W, Huezo-Diaz Patricia, Williamson Richard J, Sterne Abraham, Purcell Shaun, Hoda Farzana, Cherny Stacey S, Abecasis Gonçalo R, Prince Martin, Gray Jeffrey A, Ball David, Asherson Philip, Mann Anthony, Goldberg David, McGuffin Peter, Farmer Anne, Plomin Robert, Craig Ian W, Sham Pak C

Abstract excerpt

There is considerable evidence to suggest that the genetic vulnerabilities to depression and anxiety substantially overlap and quantitatively act to alter risk to both disorders. Continuous scales can be used to index this shared liability and are a complementary approach to the use of clinical phenotypes in the genetic analysis of depression and anxiety. The aim of this study (Genetic and Environmental Nature of...

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Identifiers

PMID: 15351774
DOI: 10.1093/hmg/ddh239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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