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Article

GENESiS: creating a composite index of the vulnerability to anxiety and depression in a community-based sample of siblings.

Twin research : the official journal of the International Society for Twin Studies - 1 Dec 2000

Sham P C, Sterne A, Purcell S, Cherny S, Webster M, Rijsdijk F, Asherson P, Ball D, Craig I, Eley T, Goldberg D, Gray J, Mann A, Owen M, Plomin R

Abstract excerpt

There is considerable evidence for a unitary and dimensional view of the genetic vulnerability to symptoms of anxiety and depression. The GENESiS (Genetic Environmental-Nature of Emotional States in Siblings) Study aims to use a multivariate approach to detect genetic loci that contribute to individual differences in this vulnerability dimension. The study used the UK General Practice Research Framework to...

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PMID: 11463153
DOI: 10.1375/136905200320565292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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