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Article

Effects of dosage and CYP2D6-mutated allele on plasma concentration of paroxetine.

European journal of clinical pharmacology - 1 Oct 2004

Sawamura Kazushi, Suzuki Yutaro, Someya Toshiyuki

Abstract excerpt

OBJECTIVE: We investigated the effect of dosages of paroxetine and cytochrome P450 (CYP) 2D6 genotypes on the plasma concentration of paroxetine in Japanese patients being treated with paroxetine. METHODS: Blood samples were collected from 73 individuals after at least 2 weeks of the same daily dose of paroxetine. The plasma paroxetine concentration was measured using HPLC, and the CYP2D6 genotypes were...

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Identifiers

PMID: 15349705
DOI: 10.1007/s00228-004-0792-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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