Article
Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence.
Microbiology (Reading, England) - 1 Sept 2004
Pascon Renata C, Ganous Tonya M, Kingsbury Joanne M, Cox Gary M, McCusker John H
Abstract excerpt
This paper describes (i) the expression profile of the methionine synthase gene (MET6) in the human pathogenic fungus Cryptococcus neoformans and (ii) the phenotypes of a C. neoformans met6 mutant. In contrast to the MET3 gene, which showed no significant change in expression in any environmental condition tested, the MET6 gene showed a substantial induction in response to methionine and a dramatic...
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