Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase activity is involved in the plasma membrane redox system required for pigment biosynthesis in filamentous fungi.

Eukaryotic cell - 1 Aug 2010

Frandsen Rasmus J N, Albertsen Klaus Selk, Stougaard Peter, Sørensen Jens L, Nielsen Kristian F, Olsson Stefan, Giese Henriette

Abstract excerpt

Methylenetetrahydrofolate reductases (MTHFRs) play a key role in biosynthesis of methionine and S-adenosyl-l-methionine (SAM) via the recharging methionine biosynthetic pathway. Analysis of 32 complete fungal genomes showed that fungi were unique among eukaryotes by having two MTHFRs, MET12 and MET13. The MET12 type contained an additional conserved sequence motif compared to the sequences of MET13 and MTHFRs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to Extracellular Space

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fusarium

Share to Gene Targeting

Share to Methionine

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Oxidation-Reduction

Share to Pigments, Biological

Source

Open in PubMed Open full text

Identifiers

PMID: 20543064
DOI: 10.1128/EC.00031-10
PMCID: PMC2918935

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase activity is involved in the plasma membrane redox system required for pigment biosynthesis in filamentous fungi.PMID 20543064Read ↗

The MET13 methylenetetrahydrofolate reductase gene is essential for infection-related morphogenesis in the rice blast fungus Magnaporthe oryzae.Semantic proximity Read ↗

Enzymatic regulation of methionine/homocysteine levels by the folate pathway dictates broad-spectrum defense in Arabidopsis.Semantic proximity Read ↗

The biosynthetic pathway for aurofusarin in Fusarium graminearum reveals a close link between the naphthoquinones and naphthopyrones.Semantic proximity Read ↗

A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life.Semantic proximity Read ↗

Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo.Semantic proximity Read ↗

Systems metabolic engineering of Bacillus subtilis for efficient biosynthesis of 5‐methyltetrahydrofolateSemantic proximity Read ↗

Methionine biosynthesis is essential for infection in the rice blast fungus Magnaporthe oryzae.Semantic proximity Read ↗

New and efficient method using Saccharomyces cerevisiae mutants for identification of siderophores produced by microorganisms.Semantic proximity Read ↗

Identification of a gene cluster responsible for the biosynthesis of aurofusarin in the Fusarium graminearum species complex.Semantic proximity Read ↗

Siderophore-iron uptake in saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters.Semantic proximity Read ↗

Plasma membrane folate transport in fungi and plants is mediated by members of the oligopeptide transporter (OPT) familySemantic proximity Read ↗

Bacterial conversion of folinic acid is required for antifolate resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.