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Article

In silico activation of KcsA K+ channel by lateral forces applied to the C-termini of inner helices.

Biophysical journal - 1 Sept 2004

Tikhonov Denis B, Zhorov Boris S

Abstract excerpt

Crystallographic studies of K(+) channels in the closed (KcsA) and open (MthK) states suggest that Gly(99) (KcsA numbering) in the inner helices serves as a gating hinge during channel activation. However, some P-loop channels have larger residues in the corresponding position. The comparison of...

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Identifiers

PMID: 15345533
DOI: 10.1529/biophysj.103.037770
PMCID: PMC1304559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15345533-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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