Article
Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase.
Genetics - 1 Aug 1998
Jacobs D, Beitel G J, Clark S G, Horvitz H R, Kornfeld K
Abstract excerpt
Genetic analysis of lin-1 loss-of-function mutations suggests that lin-1 controls multiple cell-fate decisions during Caenorhabditis elegans development and is negatively regulated by a conserved receptor tyrosine kinase-Ras-ERK mitogen-activated protein (MAP) kinase signal transduction pathway....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- DNA Primers
- DNA, Helminth
- Female
- Gene Expression Regulation
- Genes, Helminth
- Helminth Proteins
- MAP Kinase Kinase 1
- Mitogen-Activated Protein Kinase Kinases
- Molecular Sequence Data