Article
kette and blown fuse interact genetically during the second fusion step of myogenesis in Drosophila.
Development (Cambridge, England) - 1 Sept 2004
Schröter Roxane H, Lier Simone, Holz Anne, Bogdan Sven, Klämbt Christian, Beck Lothar, Renkawitz-Pohl Renate
Abstract excerpt
Drosophila myoblast fusion proceeds in two steps. The first one gives rise to small syncytia, the muscle precursor cells, which then recruit further fusion competent myoblasts to reach the final muscle size. We have identified Kette as an essential component for myoblast fusion. In kette mutants, founder cells and fusion-competent myoblasts are determined correctly and overcome the very first fusion. But then, at...
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