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Article

Surface apposition and multiple cell contacts promote myoblast fusion in Drosophila flight muscles

12 Oct 2015

Abstract excerpt

Fusion of individual myoblasts to form multinucleated myofibers constitutes a widely conserved program for growth of the somatic musculature. We have used electron microscopy methods to study this key form of cell-cell fusion during development of the indirect flight muscles (IFMs) of Drosophila melanogaster. We find that IFM myoblast-myotube fusion proceeds in a stepwise fashion and is governed by apparent cross...

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PMID: 26459604
DOI: 10.1083/jcb.201503005

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