Article
Gly145 to Arg substitution in HBs antigen of immune escape mutant of hepatitis B virus.
Biochemical and biophysical research communications - 15 May 1992
Fujii H, Moriyama K, Sakamoto N, Kondo T, Yasuda K, Hiraizumi Y, Yamazaki M, Sakaki Y, Okochi K, Nakajima E
Abstract excerpt
A Japanese child born to an HBeAg-positive carrier mother received anti-HBs immunoglobulins and a plasma-derived HBs vaccine with a poor anti-HBs-antibody response. The child, who is now 3 years old, is presently suffering from chronic hepatitis with unusual serological findings that are positive for HBsAg, anti-HBs and HBeAg, since being infected with a measles virus at 12 months of age. The nucleotide sequences...
Topics
- Amino Acid Sequence
- Arginine
- Base Sequence
- Carrier State
- DNA, Viral
- Female
- Genetic Variation
- Glycine
- Hepatitis B
- Hepatitis B Surface Antigens
- Hepatitis B Vaccines