Article
[S gene mutations in HBsAg/HBsAb double positive chronic hepatitis B patients].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Apr 2009
Zhang Zhen-hua, Peng Jing, Xia Jian-bo, Tian Yong-jun, Jiang Min, Yang Dong-liang
Abstract excerpt
OBJECTIVES: To investigate S gene mutations in HBsAg/HBsAb double positive chronic hepatitis B patients. METHODS: HBV S gene from 8 patients (Group A) with HBsAg (+)/HBsAb (+) and 9 patients (Group B) with HBsAg (+)/HBsAb (-)was amplified by polymerase chain reaction (PCR) and sequencing. Both the distribution of genotype and serotype and the rate of MHR region were compared by Fisher's exact test. The mutation...
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